eVolver Manual

eVolver is an optimization engine that evolves protein sequences to stabilize the respective structures by a variety of potentials, which are compatible with those commonly used in protein threading. The scoring function combines several energy terms: a burial potential, secondary structure preferences, a distant-dependent contact potential, sequence profiles and anti-bunching restraints.
If you use eVolver, please cite the following papers:

eVolver is available as a webserver and a standalone software distribution. Datasets are available for download from here.

eVolver is free of charge under the terms of GNU General Public License for non-commercial use. It is distributed without any warranty, but with best wishes.

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© Michal Brylinski
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