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eVolver is an optimization engine that evolves protein sequences to stabilize the respective structures by a variety of potentials, which are compatible with those commonly used in protein threading. The scoring function combines several energy terms: a burial potential, secondary structure preferences, a distant-dependent contact potential, sequence profiles and anti-bunching restraints.
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If you use eVolver, please cite the following papers:

eVolver is also available as a standalone software distribution. Datasets are available for download from here. See the manual for the details on the output file format.

eVolver is free of charge under the terms of GNU General Public License for non-commercial use. It is distributed without any warranty, but with best wishes.



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