MS Chemical Engineering
Department of Biological Sciences
401 Choppin Hall
Louisiana State University
Baton Rouge LA, 70803
Tel: (225) 578-4003
Fax: (225) 578-2597
- Computational protein modeling and Cheminformatics
- Drug discovery and design
- Virus-host Interactions
- Virus protein structure prediction
- High-performance Computing
- Bio-inspired Engineering and Design
Break down in order to build up: Decomposing small molecules for fragment-based drug design with eMolFrag. J Chem Inf Model.. In Press.
Herpes Simplex Virus Type 1 UL37 protein tyrosine residues conserved among all alphaherpesviruses are required for interactions with glycoprotein K (gK), cytoplasmic virion envelopment, and infectious virus production. J Virol. 90(22):10351-10361.. 2016.
A graph-based approach to construct target-focused libraries for virtual screening. J Cheminform. 8:14.. 2016.
Deletion of a predicted β-sheet domain within the amino terminus of herpes simplex virus glycoprotein K conserved among alphaherpesviruses prevents virus entry into neuronal axons. J Virol. 90(5):2230-9.. 2016.
The amino terminus of herpes simplex virus type-1 (HSV-1) glycoprotein K (gK) is required for virion entry via the paired immunoglobulin-like type-2 receptor alpha (PILRα). Virol J. 87(6):3305-13.. 2013.
Amino acid differences in glycoproteins B (gB), C (gC), H (gH) and L (gL) are associated with enhanced herpes simplex virus type-1 (McKrae) entry via the paired immunoglobulin-like type-2 receptor α. Virol J. 9:112.. 2012.
Nucleotide sequence of herpes simplex virus type-1 (HSV-1) McKrae glycoproteins involved in virus entry and virus-induced cell fusion - gB, gC, gD, gH, gL, gK and UL20. GenBank.. 2012.